Hyperspectral Histology

Examine tissue responses to pathogens or drugs, as well as disease progression, using IR microscopy for comprehensive hyperspectral mapping.
Understand the impact of therapeutic agents or disease at the organ level, advancing diagnostic and prognostic capabilities with non-damaging label-free hyperspectral imaging.
For hyperspectral histological imaging, the instrumentation employed is the Hyperion 3000 Vis-IR microscope mounting a large area Focal Plane Array (FPA) 128x128 pixel detector and coupled with INVENIO-R Fourier Transform Infrared Spectrometer (Bruker). The covered spectral range, 4,000-750 cm-1, allows for the analysis of the most relevant spectral bands diagnostic of tissue lipids, proteins, aminoacids and carbohydrates. Transmission and reflection acquisition modalities are foreseen, depending on the sample substrate, with a lateral resolution of some microns up to a about 1 micron.