Real-time Fluorescence Imaging of 3D Tissue Sections

Real-time imaging of fine cellular structures in 3D tissues, organoids, and whole organisms is particularly useful for applications in neuroscience, histology, and developmental biology. It is performed with the THUNDER Imager 3D Tissue that provides a powerful alternative to traditional confocal microscopy for imaging thick biological specimens.
- Instant Clarity: Unlike standard widefield systems, THUNDER uses Computational Clearing to eliminate out-of-focus blur in real-time, delivering high-contrast 3D images of deep cellular structures.
- High Sensitivity: It preserves the high photon efficiency of widefield cameras, making it ideal for low-signal samples without the photobleaching risks of laser scanning.

User Advantages
- Speed & Automation: The system automates large-scale 3D tile scanning and multi-well plate imaging, significantly increasing throughput for tissue mapping.
- Structural Detail: Optimized for revealing intricate morphologies such as axons and dendrites in neuroscience or complex architectures in organoids and tissue sections.
- Ease of Use: It integrates one-click workflows that allow researchers to transition from setup to high-resolution 3D results instantly, even with large data volumes.