Cell-based Arrayed Functional Screening

A wide range of human and mouse libraries are available for functional cellular studies.

Service option:

Available Arrayed libraries in 384 format:
1) Human whole-genome siRNA library (Dharmacon ON-TARGETplus®) – cherry-picking available for custom sub-library development
2) Mouse whole-genome siRNA library (Dharmacon SmartPool) – cherry-picking available for custom sub-library development
3) Human microRNA mimics library (Dharmacon, miRBase v21)
4) Mouse microRNA inhibitors library (Dharmacon, miRBase v21)

Option 1: Image-based phenotypic screening. Automated confocal fluorescence imaging combined with automated image analysis and quantitative feature extraction. Data are generated at the single-cell level and can be exported at both cell-level and well-level resolution. Allows kinetic multi time point measurement of live cells if needed.

Option 2: Biochemical assays. Fluorescence-, absorbance-, and chemiluminescence-based assays compatible with measurements of enzymatic
activity, gene expression, protein synthesis, and cell viability. Data are reported as well-averaged measurements.

For further information and contacts: https://www.icgeb.org/high-throughput-screening-equipment/