AFM-based Nanoindentation

Controlling shallow indentation depth, load, and effective contact volume, AFM-based nanoindentation has application in surface height topology mapping and 3D high-resolution imaging.
It is commonly used to analyse the physical properties of soft solids, such as biological samples (e.g. tissues, spheroids, organoids), biocompatible scaffolds (e.g. polymers, hydrogels) and bioimprinted materials.
The instrumentation employed for micro-to- nanoindentation analysis encompasses Chiaro Nanoindenter and AFM, the former being more high throughput while the latter allowing mapping sub-cellular structures' biomechanical traits.