Overview: Identifying and quantifying prognostic and diagnostic biomarkers for different diseases, including oncological and viral pathologies, for clinical trials support.
Perform targeted or untargeted analysis of endogenous and exogenous metabolites with applications in:
Therapy evaluation: monitoring the effectiveness of therapies and deciphering drug mechanisms, safety profiles, or toxicity.
Patient response analysis: identifying responder and non-responder patients to tailor personalized treatment approaches.
Drug action mechanisms: supporting the development of new drugs by understanding their mechanisms of action.
Workflow: Metabolome extraction, profiling by UHPLC-HRMS (either HILIC or RP), pre-processing using Compound Discoverer or Additional open access tools, data analysis with in house script and algorithms.
Services Options:
- Untargeted analysis
- Targeted analysis