Multi-Omics Platform
Pharmacokinetic Studies, Services options: Data interpretation
Overview: Assisting pharmaceutical chemists in the transition of compounds from initial hits to lead candidates. Our services include:
Workflow:
In vitro and in vivo ADMET simulation: using immobilized artificial membranes, hepatic microsomes from various species, and plasma protein binding assays.
Metabolite identification: detecting unknown metabolites, assessing drug metabolization levels, and conducting in vivo biodistribution studies using animal plasma.
Stability tests: evaluating drug stability under various stress conditions such as chemical stress, UV light, and temperature changes. Profiling with UHPLC-HRMS of drugs or metabolites.
Service Options:
- Untargeted analysis
- Targeted analysis
